McCarthy TeamPublications
Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA.
Kowalinski, E., Lunardi, T., McCarthy, A.A., Louber, J., Brunel, J., Grigorov, B., Gerlier, D. & Cusack, S.
Cell. 2011 Oct 14;147(2):423-35. PubMed
Translation calibration of inverse-kappa goniometers in macromolecular crystallography.
Brockhauser, S., White, K.I., McCarthy, A.A. & Ravelli, R.B.
Acta Crystallogr A. 2011 May;67(Pt 3):219-28. Epub 2011 Mar 15. PubMed
Visualizing the metal-binding versatility of copper trafficking sites .
Badarau, A., Firbank, S.J., McCarthy, A.A., Banfield, M.J. & Dennison, C.
Biochemistry. 2010 Sep 14;49(36):7798-810. PubMed
MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments.
Gabadinho, J., Beteva, A., Guijarro, M., Rey-Bakaikoa, V., Spruce, D., Bowler, M.W., Brockhauser, S., Flot, D., Gordon, E.J., Hall, D.R., Lavault, B., McCarthy, A.A., McCarthy, J., Mitchell, E., Monaco, S., Mueller-Dieckmann, C., Nurizzo, D., Ravelli, R.B., Thibault, X., Walsh, M.A., Leonard, G.A. & McSweeney, S.M.
J Synchrotron Radiat. 2010 Sep;17(5):700-7. Epub 2010 Jul 13. PubMed
Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain.
Hinz, A., Miguet, N., Natrajan, G., Usami, Y., Yamanaka, H., Renesto, P., Hartlieb, B., McCarthy, A.A., Simorre, J.P., Gottlinger, H. & Weissenhorn, W.
Cell Host Microbe. 2010 Apr 22;7(4):314-23. PubMed
A decade of user operation on the macromolecular crystallography MAD beamline ID14-4 at the ESRF.
McCarthy, A.A., Brockhauser, S., Nurizzo, D., Theveneau, P., Mairs, T., Spruce, D., Guijarro, M., Lesourd, M., Ravelli, R.B. & McSweeney, S.
J Synchrotron Radiat. 2009 Nov;16(Pt 6):803-12. Epub 2009 Oct 7. PubMed
The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit.
Dias, A., Bouvier, D., Crepin, T., McCarthy, A.A., Hart, D.J., Baudin, F., Cusack, S. & Ruigrok, R.W.
Nature. 2009 Apr 16;458(7240):914-8. Epub 2009 Feb 4. PubMed
Capturing the Shape of Macromolecular Crystals in 3D
Leal, R.M.F. Teixeira, S.C.M. Rey, V. Forsyth, V.T. Mitchel, E.P. Brockhauser, S. Di Michiel, M. McGeehan, J.E. McCarthy, A., Ravelli, R.B.G
ESRF Highlights 2008, 127-129
X-ray tomographic reconstruction of macromolecular samples.
Brockhauser, S., Di Michiel, M. McGeehan, J. E., McCarthy, A. A., Ravelli, R. B. G.
J. Appl. Cryst. 2008 41 1057-1066
Structural insights into the Slit-Robo complex.
Morlot, C., Thielens, N.M., Ravelli, R.B., Hemrika, W., Romijn, R.A., Gros, P., Cusack, S. & McCarthy, A.A.
Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14923-8. Epub 2007 Sep 11. PubMed
Production of Slit2 LRR domains in mammalian cells for structural studies and the structure of human Slit2 domain 3.
Morlot, C., Hemrika, W., Romijn, R.A., Gros, P., Cusack, S. & McCarthy, A.A.
Acta Crystallogr D Biol Crystallogr. 2007 Sep;63(Pt 9):961-8. Epub 2007Aug 17. PubMed
Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase.
Martinez Molina, D., Wetterholm, A., Kohl, A., McCarthy, A.A., Niegowski, D., Ohlson, E., Hammarberg, T., Eshaghi, S., Haeggstrom, J.Z. & Nordlund, P.
Nature. 2007 Aug 2;448(7153):613-6. Epub 2007 Jul 15. PubMed
Cloning, expression, crystallization and preliminary X-ray analysis of the first two Ig domains from human roundabout 1 (Robo1).
Morlot, C., Hemrika, W., Romijn, R.A., Gros, P., Cusack, S. & McCarthy, A.A.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt8):689-91. Epub 2007 Jul 21. PubMed
The structure of two N-methyltransferases from the caffeine biosynthetic pathway.
McCarthy, A.A. & McCarthy, J.G.
Plant Physiol. 2007 Jun;144(2):879-89. Epub 2007 Apr 13. PubMed
Cloning, expression, crystallization and preliminary X-ray analysis of the XMT and DXMT N-methyltransferases from Coffea canephora (robusta).
McCarthy, A.A., Biget, L., Lin, C., Petiard, V., Tanksley, S.D. & McCarthy, J.G.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt4):304-7. Epub 2007 Mar 12. PubMed
Plastic-embedded protein crystals.
Ravelli, R.B., Haselmann-Weiss, U., McGeehan, J.E., McCarthy, A.A., Marquez, J.A., Antony, C., Frangakis, A.S. & Stranzl, G.
J Synchrotron Radiat. 2007 Jan 1;14(Pt 1):128-32. Epub 2006 Dec 15. PubMed
Structure of Dimeric SecA, the Escherichia coli Preprotein Translocase Motor.
Papanikolau, Y., Papadovasilaki, M., Ravelli, R.B., McCarthy, A.A., Cusack, S., Economou, A. & Petratos, K.
J Mol Biol. 2006 Dec 23;. PubMed
Structure of C3b reveals conformational changes that underlie complement activity.
Janssen, B.J., Christodoulidou, A., McCarthy, A., Lambris, J.D. & Gros, P.
Nature. 2006 Nov 9;444(7116):213-6. Epub 2006 Oct 15. PubMed
Structural analysis of Bordetella pertussis BugE solute receptor in a bound conformation.
Huvent, I., Belrhali, H., Antoine, R., Bompard, C., Locht, C., Jacob-Dubuisson, F. & Villeret, V.
Acta Crystallogr D Biol Crystallogr. 2006 Nov;62(Pt 11):1375-81. Epub 2006Oct 18. PubMed
High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline.
Beteva, A., Cipriani, F., Cusack, S., Delageniere, S., Gabadinho, J., Gordon, E.J., Guijarro, M., Hall, D.R., Larsen, S., Launer, L., Lavault, C.B., Leonard, G.A., Mairs, T., McCarthy, A., McCarthy, J., Meyer, J., Mitchell, E., Monaco, S., Nurizzo, D., Pernot, P., Pieritz, R., Ravelli, R.G., Rey, V., Shepard, W., Spruce, D., Stuart, D.I., Svensson, O., Theveneau, P., Thibault, X., Turkenburg, J., Walsh, M. & McSweeney, S.M.
Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1162-9. Epub 2006Sep 19. PubMed
The care and nurture of undulator data sets.
Flot, D., Gordon, E.J., Hall, D.R., Leonard, G.A., McCarthy, A., McCarthy, J., McSweeney, S., Mitchell, E., Nurizzo, D., Ravelli, R.B.G. & Shepard, W.
Acta Crystallogr D Biol Crystallogr. 2006 Jan;62(Pt 1):65-71. Epub 2005Dec 14. PubMed
Automation of macromolecular crystallography beamlines.
Arzt, S., Beteva, A., Cipriani, F., Delageniere, S., Felisaz, F., Forstner, G., Gordon, E., Launer, L., Lavault, B., Leonard, G., Mairs, T., McCarthy, A., McCarthy, J., McSweeney, S., Meyer, J., Mitchell, E., Monaco, S., Nurizzo, D., Ravelli, R.B.G., Rey, V., Shepard, W., Spruce, D., Svensson, O. & Theveneau, P.
Prog Biophys Mol Biol 2005 Oct;89(2):124-52. PubMed
Structure and function of the C-terminal domain of the polymerase cofactor of rabies virus.
Mavrakis, M., McCarthy, A.A., Roche, S., Blondel, D. & Ruigrok, R.W.
J Mol Biol 2004 Oct 29;343(4):819-31. PubMed
Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes.
Harel, M., Aharoni, A., Gaidukov, L., Brumshtein, B., Khersonsky, O., Meged, R., Dvir, H., Ravelli, R.B., McCarthy, A., Toker, L., Silman, I., Sussman, J.L. & Tawfik, D.S.
Nat Struct Mol Biol 2004 May;11(5):412-9. Epub 2004 Apr 18. PubMed
Crystal structure of MshB from Mycobacterium tuberculosis, a deacetylase involved in mycothiol biosynthesis.
McCarthy, A.A., Peterson, N.A., Knijff, R. & Baker, E.N.
J Mol Biol 2004 Jan 23;335(4):1131-41. PubMed