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Instrumentation at the EMBL Grenoble outstation
At the EMBL Grenoble, the Diffraction Instrumentation Team develops instruments for Macromolecular X-ray crystallography, neutron crystallography and Small Angle X-ray Scattering experiments, strongly involving the Synchrotron Crystallography and High Throughput Crystallisation teams. Current focus is on beamline automation, diffractometers for micro-crystals and automation of crystal harvesting. Several projects are developed in collaboration with the ESRF Structural Biology Group and with EMBL@PETRA-III. Most of the instruments developed are commercially available from Bruker-asc, Maatel scientific-instrumentation, Cedrat, Molecular Dimensions, Hampton Research or Mitegen.
Contact: Instrumentation
On the workbench
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MD3 vertical Kappa Diffractometer In collaboration with EMBL@PETRA-III MX2 beamline, Gleb Bourenkov.
Download the video "MD3_SOC-1" - Kappa = 0°, Omega 160°/s; Glass needle 0.3 µm tip; Scale 1 µm/div
Download the video "MD3_SOC-2" - Kappa = 48°, Omega 20°/sec; Glass needle 1 µm hole; Scale 10 µm/div
Download the video "MD3_4Dscan" - Needle Ø8 µm X 150 µm; 4D scan: 180°, 18°/s; Scale 10 µm/div
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CrystalDirectJointly with the Grenoble HTX Team, J.A. Marquez
In-plate crystal screening & automated harvesting
Download the video "CD_LaserHarvesting"
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NewPinSupported by BioStruct-X
Tentative for a new European sample holder standard
Download the video "Repositioning precision"
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Instruments for Macromolecular X-ray crystallography and SAXS experiments
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BioSAXS automated sample environment
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HC1 Crystal Humidity Control
ESRF, Diamond, MAX-Lab, Bessy, CLS
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Collaboration link
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Sample
Changer SC3, download a video load/unload 1 sample (real time) 4.3 Mb
ESRF
ID14-1, ID14-2, ID14-3, ID14-4, ID29, ID23-1, ID23-2 ; embl-France ESRF BM14 CRG |
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Mini
Kappa Goniometer Head, download videos
ESRF ID14-4,
ID29, ID23-1; embl-France ESRF BM14 CRG, ESRF BM30 CEA-IBS CRG, APS LS CAT; Diamond; ALS; Bessy |
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Microspectrophotometer,
ESRF ID14-x
Use it at the ESRF
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MD2M
Diffractometer (Minidiffractometer)
ESRF ID14-1,
ID14-2, ID14-4, ID29, ID23-1, ID23-2 |
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MD2 Diffractometer (Microdiffractometer)
SLS X06S; ESRF
ID14-3; embl-France ESRF BM14 CRG; APS NE CAT, LS CAT; Bessy, ALS, CLS, SSRL, EMBL-HH, Alba, MAX-lab, Soleil |
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Automatic
Crystal Alignment Library C3D
ESRF
ID14-1, ID14-2, ID14-3, ID14-4, ID29, ID23-1, ID23-2 ; EMBL/ESRF BM14 (CRG); NSLS |
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On Axis
Video-microscope
ESRF BM30 FIP
CNRS/IBS GRG + EMBL/ESRF BM14 (CRG); NSLS |
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Piezoelectric Shutter, download a video 1" exposure 5 passes ( real time 5 x
0.2") 215Kb
ESRF ID14-1,
ID14-2, ID14-3, ID14-4, ID29, ID23-1, ID23-2; APS NE-CAT, EMBL-HH |
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Neutron diffractometers
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FINDER
(VIVALDI)
ILL VIVALDI,
LADI3; ANSTO (KOALA); FRMII (QLD); Oak Ridge National Lab (LADI-III) |
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