EMBO Practical Course on the "Structural Characterization of Macromolecular Complexes"

Date : May 15-20, 2006

Location: EMBL Grenoble Outstation & ESRF, Grenoble, France

Organisers:

• Christoph W. Müller (EMBL)
• Stephen Cusack (EMBL)
• Elspeth Gordon (ESRF)
• Darren Hart (EMBL)
• Jose Marquez (EMBL)
• Carlo Petosa (EMBL)
• Guy Schoehn (IVMS)
• Winfried Weissenhorn (EMBL)

Summary:

The course will cover strategies and techniques required to produce, purify, and characterize multi-protein and protein/nucleic acid complexes.

Topics include: the production of complex components in bacteria, yeast, insect and mammalian cells; isolation of complexes using affinity purification techniques; biocomputational, biochemical and biophysical characterization; and structural characterization by X-ray crystallography, NMR, cryo-EM, and small angle X-ray or neutron scattering. The course is mainly directed at senior Ph.D students and post-docs working in structural biology.

Course Program: HTML / PDF

Practical sessions

Instructors include:

• Patrick Aloy (IRB, Barcelona)
• Nick Berrow (Oxford U.)
• Michela Bertero (Gene Centre, U. of Munich)
• Bettina Böttcher (EMBL, Heidelberg)
• Stephanie Cabantous (Los Alamos National Laboratory)
• Christine Ebel (IBS, Grenoble)
• Achilles Frangakis (EMBL, Heidelberg)
• Anne-Claude Gavin (EMBL, Heidelberg)
• Wieger Hemrika (Utrecht University)
• Iain Jones (U. of Reading)
• Gordon Leonard (ESRF, Grenoble)
• Kiyoshi Nagai (MRC-LMB, Cambridge)
• Jorge Navaza (IBS, Grenoble)
• Luca Pellegrini (U. of Cambridge)
• Vladimir Rybin (EMBL, Heidelberg)
• Michael Sattler(EMBL, Heidelberg)
• Bertrand Séraphin (CNRF, Gif sur Yvette)
• Holger Stark (Max Planck Inst., Götingen)
• Dimitri Svergun (EMBL, Hamburg)
• Song Tan (Pennsylvania State U.)
• Willy Wriggers (U. of Texas Health Science Center)
• Min Zhou (U. of Cambridge)

Subscriptions to this course are now closed

DEADLINE FOR APPLICATION: March 15, 2006

Previous course: EMBO 2004

In case of questions contact the course secretary Mary-Jane Villot (villot@embl.fr) or Christoph W. Müller (mueller@embl.fr).